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Ocular Cicatricial Pemphigoid An 83-year-old monocular male presented to the Cornea division, Bascom Palmer Eye Institute with bilateral decreased vision, pain redness and burning for many years getting progressively worse. Examination revealed hand motion vision, ankyloblepharon and chronic cicatr…

Autosomal Recessive RPE65-Deficient Leber Congenital Amaurosis A 17-year-old male with a biallelic RPE65 mutation resulting in autosomal recessive Leber Congenital Amaurosis is referred for evaluation for subretinal gene therapy with voretigene neparvovec-rzyl. Baseline evaluation was remarkable fo…

Autosomal Recessive RPE65-Deficient Leber Congenital Amaurosis A 17-year-old male with a biallelic RPE65 mutation resulting in autosomal recessive Leber Congenital Amaurosis is referred for evaluation for subretinal gene therapy with voretigene neparvovec-rzyl. Baseline evaluation was remarkable fo…

Extranodal Rosai-Dorfman Disease A 28-year-old male without past medical history presented with a 1 year history of painless bilateral upper lid swelling. After multimodal imaging studies, the patient underwent diagnostic orbital biopsy. The pathologic analysis of the biopsy showed a plasmacytic in…

Extranodal Rosai-Dorfman Disease A 28-year-old male without past medical history presented with a 1 year history of painless bilateral upper lid swelling. After multimodal imaging studies, the patient underwent diagnostic orbital biopsy. The pathologic analysis of the biopsy showed a plasmacytic in…

Severe Non-Proliferative Diabetic Retinopathy with Cystoid Macular Edema A 65-year-old male with diabetic retinopathy and CME presented to the BPEI retina clinic for continued management of his chronic ocular condition. His care was complicated by an inability to submit to ocular examinations in th…

Severe Non-Proliferative Diabetic Retinopathy with Cystoid Macular Edema A 65-year-old male with diabetic retinopathy and CME presented to the BPEI retina clinic for continued management of his chronic ocular condition. His care was complicated by an inability to submit to ocular examinations in th…

Central Serous Retinopathy A 48-year-old female presents with a history of chronically decreased vision in her right eye. Multimodal imaging reveals serous macular detachment, thickened choroid, and focal areas of late leakage on fluorescein angiography. The left eye has pigmentary changes in the p…

Central Serous Retinopathy A 48-year-old female presents with a history of chronically decreased vision in her right eye. Multimodal imaging reveals serous macular detachment, thickened choroid, and focal areas of late leakage on fluorescein angiography. The left eye has pigmentary changes in the p…

Ocular Ischemic Syndrome Ocular ischemic syndrome (OIS) is a rare condition associated with severe carotid artery occlusive disease leading to ocular hypoperfusion. It typically presents at mean age of 65, there is no racial predilection, and is two times more common in men than women. It is typica…

Ocular Ischemic Syndrome Ocular ischemic syndrome (OIS) is a rare condition associated with severe carotid artery occlusive disease leading to ocular hypoperfusion. It typically presents at mean age of 65, there is no racial predilection, and is two times more common in men than women. It is typica…

Retinopathy of Prematurity An 19-year-old woman presented with decreased vision in the right eye and was found to have a retinal detachment. She had a history of retinopathy of prematurity as an infant and had been treated with laser photocoagulation. Treatment for retinopathy of prematurity in the…

Retinopathy of Prematurity An 19-year-old woman presented with decreased vision in the right eye and was found to have a retinal detachment. She had a history of retinopathy of prematurity as an infant and had been treated with laser photocoagulation. Treatment for retinopathy of prematurity in the…

Sterile Endophthalmitis Post-injection sterile endophthalmitis is an acute intraocular inflammation of the vitreous cavity that resolves without the need of intravitreal antibiotics and/or vitreoretinal surgery. Differentiating between infectious and sterile endopthalmitis is often difficult and no…

Sterile Endophthalmitis Post-injection sterile endophthalmitis is an acute intraocular inflammation of the vitreous cavity that resolves without the need of intravitreal antibiotics and/or vitreoretinal surgery. Differentiating between infectious and sterile endopthalmitis is often difficult and no…

Pseudoangiomatous Retinal Gliosis A 54-year-old Hispanic male presented with decreased vision in the right eye over 3 months. Dilated fundus exam of the right eye showed a geographic area of chorioretinal alteration in the far temporal periphery at 9 o’clock, a gliovascular retinal mass superiorl…

Pseudoangiomatous Retinal Gliosis A 54-year-old Hispanic male presented with decreased vision in the right eye over 3 months. Dilated fundus exam of the right eye showed a geographic area of chorioretinal alteration in the far temporal periphery at 9 o’clock, a gliovascular retinal mass superiorl…

Conjunctival Keratoacanthoma Keratoacanthoma (KA) is an epithelial tumor characterized by rapid, abundant growth and a potential for spontaneous resolution. It typically occurs on the skin in sun-exposed areas such as the face, neck, and hands. Rarely it can occur on the conjunctiva and vulvar regi…

Conjunctival Keratoacanthoma Keratoacanthoma (KA) is an epithelial tumor characterized by rapid, abundant growth and a potential for spontaneous resolution. It typically occurs on the skin in sun-exposed areas such as the face, neck, and hands. Rarely it can occur on the conjunctiva and vulvar regi…

Abstract A 57-year-old woman with PMH of hyperthyroidism presents with eye pain, swelling, and blurry vision worsening for 3 weeks. Exam revealed severe proptosis, exposure keratopathy, orbital congestion, and markedly reduced visual acuity. CT and laboratory were workup consistent with sight-threa…