Retina and Vitreous Diseases

Radiation Retinopathy A patient with past medical history of CNS lymphoma treated with chemotherapy but refractory and necessitating radiation therapy later presented to ophthalmology with slight decrease in vision. On examination, found to have cotton wool spots in both eyes. Fluorescein angiogram…

Penetrating Open Globe Injury with Retained Intraocular Foreign Body, Left Eye A patient presented with acute decreased vision in the left eye after motor vehicle accident. The patient stated in the accident his car spun out and airbags deployed. Upon presentation, visual acuity was 20/25 in the ri…

Endogenous Endophthalmitis A middle-aged patient presented to the ophthalmology emergency department with 1-day of blurred vision in his left eye. He reported fevers the week prior. Examination of the left eye was remarkable for a subretinal abscess with hemorrhage, vasculitis, and a preretinal hyp…

Retinal Detachment in Proliferative Sickle Cell Retinopathy A middle-aged patient presented with decreased vision in her right eye. She had a history of proliferative sickle cell retinopathy. She is blind in the left eye from a prior failed retinal detachment repair. Her vision in the right eye was…

A patient presented with a central scotoma in the right eye. Fundus examination revealed midperipheral chorioretinal atrophy in both eyes (Fig A). Fundus autofluorescence demonstrated areas of confluent midperipheral hypoautofluorescence (Fig B). Optical coherence tomography demonstrated choroidal …

Vitelliform Maculopathy A middle-aged patient with a remote history of prostate cancer in remission presented as a referral for evaluation of retinal lesions. He denied any complaints initially. He was noted to have orangeish vitelliform lesions deposited around his vascular arcades. Workup for oth…

Choroideremia with Secondary Choroidal Neovascularization A patient with no past medical history presented to the emergency department complaining of floaters in the right eye. Exam was notable for visual acuity of 20/70 in the right eye and 20/30 in the left eye. Intraocular pressures were 14 and …

Bardet-Biedl Syndrome A young adult presented with progressive decrease in the visual acuity of both eyes. Past medical history included idiopathic intracranial hypertension suspect, obesity, learning disabilities, anxiety, polydactyly (status post excision of an extra toe). Family history includes…

Acute Zonal Occult Outer Retinopathy (AZOOR) A patient with a history of photopsias in the left eye for approximately 20 years comes for evaluation due to photopsias now involving both eyes. Concomitantly, the patient also notices scotomas in both eyes. Infectious, immune, and degenerative retinopa…

Acute Macular Neuroretinopathy A young patient presents with acute onset of blurry vision and scotoma. Visual acuity is 20/25 in both eyes. Exam reveals hypopigmented patches in the macula of both eyes, as well as a flame hemorrhage in the left. Imaging reveals disruption of the outer plexiform, ou…

A young patient presented with a 1-week history of unilateral superior visual field deficit in the left eye with a visual acuity of 20/30 with pinhole correction to 20/20, normal IOP, and without an APD. Detailed medical, surgical, family, and social history-taking revealed only patient consumption…

Fundus photo of Central Retinal Artery Occlusion (CRAO).

Central Retinal Artery Occlusion An elderly patient presented to the BPEI Emergency Room 3 hours after onset of painless vision loss. Past medical history included hypertension and atrial fibrillation treated with apixaban, of which the patient reported good adherence. The patient had no other sign…

OCTA demonstrating neovascularization (yellow arrow) growing into the vitreous with widefield imaging.

This patient was diagnosed with genetic testing to have the hereditary vitreoretinopathy, Wegner's Syndrome. The abnormal vitreoretinal interface leads to a focal tractional retinal detachment of the macula. Post-operative photo and OCT show resolution of the detachment after vitrectomy.

Vitreous Hemorrhage A patient with a past medical history of hypertension presented with vision loss in the right eye for two days. His exam was notable for visual acuity of hand motions in the right eye and 20/20 in the left eye. Intraocular pressures and slit lamp exam were normal in both eyes. P…

Vitreous Amyloidosis A patient presented to clinic with four months of blurry vision in the right eye. Of note, patient had previous vitrectomy for vitreous floaters of the left eye and panretinal photocoagulation in both eyes for retinal neovascularization. Examination of the right eye revealed de…