Ocular Oncology

Invasive Cutaneous Melanoma of the Eyelid A patient presented to clinic for a long-standing history of a left lower eyelid/ cheek lesion with more recent growth. He had a history of multiple previously resected basal cell carcinomas of the face, neck and scalp. Initial examination was notable a lef…

Adult-Onset Asthma with Periocular Xanthogranuloma A patient with a history of asthma and chronic sinusitis presented with unilateral facial swelling for three years. The facial swelling had gradually worsened over time. On examination, a well demarcated, yellow lesion was present in the right eyel…

Recurrent Locally Advance Morpheaform BCC A patient presented to our clinic with a 5 month history of worsening ptosis and induration of the right upper eyelid. She had a past medical history significant for chronic UV exposure, and a previously completely excised infiltrating/morpheaform basal cel…

Granular Cell Tumor A patient was referred by an outside ophthalmologist for evaluation. The patient reported having headaches, double vision, and eye bulging for 3 months. Her exam was notable for restricted extraocular movements in her left eye on abduction and adduction. Her slit lamp exam was n…

Multimodal imaging of a patient with ciliochoroidal melanoma with extraocular extension associated with sympathetic ophthalmia before and after treatment.

Choroidal Metastasis A patient presented to the Bascom Palmer Eye Institute with blurred vision in the left eye for 5 days. Past medical and ocular history was unremarkable. Past social history was notable for 25 pack-year smoking history. Visual acuity in the right eye was 20/20. Visual acuity in …

Ciliochoroidal Melanoma with Extraocular Extension Complicated by Sympathetic Ophthalmia A patient presented with a pigmented conjunctival lesion in the right eye of insidious onset and progressive course. She was found to have a ciliochoroidal melanoma with extraocular extension and underwent exci…

Squamous Cell Carcinoma of the Lacrimal Sac A patient presented to the emergency department for a history of tearing on the right eye and medial canthal mass. He had a history of chronic sinus pain for months, initial examination was notable for increased tear lake on the right eye, along with an i…

Acute Myeloid Leukemia A previously healthy child presented with bilateral periorbital edema, right greater than left proptosis, with generalized facial swelling and copious nasal discharge, not improved on antibiotics. Imaging revealed multiple extraconal soft tissue masses in the orbits bilateral…

Conjunctival melanoma treated with I-125 brachytherapy.

This patient presented with 1 month of left eyelid swelling. MRI showed infiltration in the periorbital soft tissues. Absolute CD4 count was 27 and the diagnosis was made with immunohistochemistry positive for HHV8. The patient was started on HAART therapy, the local lesions were treated with nitro…

Orbital Rhabdomyosarcoma - Recurrence A young patient with notable past ocular history of orbital rhabdomyosarcoma, s/p chemotherapy with vincristine, dactinomycin, and cyclophosphamide, and proton beam radiation presented to Bascom Palmer ED with 2 days of blurry vision and “seeing everything gr…

Fundus photo of a patient showing a choroidal melanocytic lesion of the macula with subretinal fluid and orange pigment. The patient has a history of metastatic cutaneous melanoma.

Choroidal Metastases from Cutaneous Melanoma A patient with history of cutaneous melanoma presents with worsening vision of the right eye over a period of a few weeks. His exam was notable for visual acuity of 20/40 in the right eye and 20/25 in the left eye. Intraocular pressure was 18 in both eye…

Conjunctival Melanoma Two darkly pigmented patients with a diagnosis of conjunctival melanoma by an outside provider are presented here. Case 1 presented with a large jet black conjunctival lesion that was present for nearly 12 years. This lesion was biopsied by an outside provider and interpreted …

Metastatic Melanoma; Side Effect of Immune Checkpoint Inhibitor A patient with a history of recurrent metastatic conjunctival melanoma presented with a left upper lid orbital lesion and pigmented lesion in the medial fornix. The original conjunctival melanoma was originally excised in an outside ce…

Diffuse Iris Melanoma A patient presented for evaluation of multiple melanocytic lesions of the right iris that were noticed a few months prior. She was found to have a visual acuity of 20/25 in the right eye and 20/20 in the left eye, with intraocular pressures of 19mmHg in both eyes. Slit lamp ex…

Orbital Sarcoidosis A patient presented with three months of left eye swelling and pain. He was found to have periorbital firmness and fullness, proptosis, and conjunctival chemosis. He underwent computed tomography imaging of the orbits with contrast, which demonstrated an ill-defined, irregular a…