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Ocular Surface Squamous Neoplasia A 71-year-old male with a history of atopic dermatitis was referred to BPEI for evaluation of a corneal lesion. Exam revealed an opalescent and gelatinous lesion at 2-4 o'clock at the limbus in the left eye. Anterior segment OCT showed a thickened, hyperreflective …

Ocular Surface Squamous Neoplasia A patient presented to BPEI for a cornea evaluation with blurred vision, foreign body sensation and redness for 1 year duration. The exam was notable for visual acuity of 20/150 in the right eye. Intraocular pressure was 8 in the right eye, Slit lamp exam was most …

Ocular Surface Squamous Neoplasia An elderly patient with a diffuse ocular surface squamous neoplasia (OSSN) of the left eye is treated with cycles of Interferon, 5 Fluorouracil and Mitomycin C topical chemotherapy without improvement. Due to high out-of-pocket costs and epiltheliopathy after 7 mon…

Ocular Surface Squamous Neoplasia A patient with an ocular history of OSSN presents with several months of monocular double vision in his right eye. He states that symptoms came on slowly and have progressively gotten worse. His exam was notable for a vision of 20/150 in the right eye that pin-hole…

A patient with severe limbal stem cell defiency due to extensive tumor excision undergoes ocular surface reconstruction and SLET.

Ocular Graft Versus Host Disease A 39-year-old female with 6 months of eye itchiness and yellow discharge for 6 months. Pt has a history of acute lymphoblastic leukemia treated with allogenic bone marrow transplant. Pt diagnosed with ocular graft versus host disease. Pt had some improvement with lu…

Ocular Cicatricial Pemphigoid / Mucous Membrane Pemphigoid A patient with a PMHx of HTN presented to BPEI with redness and discharge of the left eye for 3 months. Review of systems was negative for any systemic symptoms. Visual acuity of the left eye was 20/80, IOP was 13 mmHg, there was no APD, an…

Ocular Cicatricial Pemphigoid An 83-year-old monocular male presented to the Cornea division, Bascom Palmer Eye Institute with bilateral decreased vision, pain redness and burning for many years getting progressively worse. Examination revealed hand motion vision, ankyloblepharon and chronic cicatr…

Ocular Cicatricial Pemphigoid An elderly patient with severe ocular cicatricial pemphigoid (OCP) and immunosuppressed with mycophenolate mofetil has previously lost the right eye due to corneal perforation and choroidal hemorrhage resulting in evisceration. After 5 years of quiescence, his left eye…

Ocular cicatricial pemphigoid with symblepharon in both eyes.

Nontuberculous Mycobacterium Keratitis A 39-year-old Hispanic male presented to the Emergency Room with worsening blurry vision and pain in the left eye for 1 month after feeling something “fly into his eye” while cutting wood. Visual acuity was 20/40 on presentation with a small 1 x 1 mm multi…

Nontuberculous Mycobacterial Keratitis A patient with past ocular history of uncomplicated pterygium surgery develops mycobacterial keratitis which progresses to a descemetocele. After worsening on topical antibiotics to the point of nearly perforating, the patient undergoes rose-Bengal photodynami…

Nontuberculous Mycobacteria Keratitis A patient five months after bilateral simultaneous cataract surgery in another country presents to the BPEI emergency room with bilateral decreased vision and extreme right eye pain for the last 2 weeks. Their exam was notable for visual acuity of hand motion i…

Non-Infectious Scleritis A monocular patient admitted for pyoderma gangrenosum flare complained of decreased vision and left eye pain. Four years prior she had scleritis OD which requiring scleral reinforcement surgery after which the patient was lost to follow up, developed endophthalmitis and eve…

Slit lamp photos of non-infectious necrotizing scleritis at presentation, week 4, 7, 9.5, and 12 of treatment with systemic corticosteroids and rituximab.

Nocardia Amikacinitolerans Corneal Ulcer A 31-year-old male presented to the Bascom Palmer Eye Institute ER with six weeks of decreased vision in the right eye. Examination revealed 20/70 vision, a white and quiet eye, with a stromal corneal infiltrate and elevated IOP. The patient was treated with…

Neurotrophic Keratitis A patient presented to the Bascom Palmer Eye Institute’s emergency room with acute on chronic left eye pain. The history was notable for a left petroclival chondrosarcoma that had been resected with post-operative, left-sided cranial nerve 5, 6, 7 and 8 palsies. The patient…

The patient presented with a neurotrophic corneal ulcer and descemetocele. A lamellar keratectomy, corneal patch graft, amniotic membrane were applied. Preop and post-op-month 1, with amniotic membrane dissolved.

Mycoplasma Pneumoniae-Induced Rash and Mucositis (MIRM) A patient presented to BPEI ED with dysuria x4 days and worsening red eye and irritation OU x2 days. Diagnosed with possible STI + conjunctivitis by outside Urgent Care 2 days prior. On our examination, he had decreased BCVA of 20/50 OD and 20…

Mycobacterium Abscessus Keratitis A patient was referred for management of a corneal ulcer in their right eye. Initial exam revealed VA OD CF with diffuse corneal epithelial defect, infiltrate, and endothelial plaque and anterior inflammation with a hypopyon. Corneal cultures were positive for Myco…