Topic outline

  • Grand Rounds

    A 71-year-old male with a history of atopic dermatitis was referred to BPEI for evaluation of a corneal lesion. Exam revealed an opalescent and gelatinous lesion at 2-4 o'clock at the limbus in the left eye. Anterior segment OCT showed a thickened, hyperreflective epithelium with an abrupt transition. Biopsy confirmed ocular surface squamous neoplasia. He was treated with a four-week course of 5-fluorouracil, and complete resolution of the lesion was obtained. However, two years later he presented with recurrence. He was again treated with 5-fluorouracil, however the lesion did not completely regress. He was then treated with surgical excision and cryotherapy and is now in complete remission. His treatment course is documented in this presentation.

    Presentation Date: 09/10/2020
    Issue Date: 02/12/2021