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Acute Posterior Multifocal Placoid Pigment Epitheliopathy A patient presented with one week of blurred vision. He noted a concomitant headache and cold symptoms as well. He had a history of IV drug use 10 days prior. His visual acuity was 20/100 in the right eye and 20/20 in the left eye. Examinati…

Fundus photo demonstrating confluent creamy yellow-white lesions representing acute posterior multifocal placoid pigment epitheliopathy.

Acute Retinal Necrosis A monocular patient with no past ocular history in the left eye presented with several days of decreased vision in the left eye. On examination he was found to have panuveitis, and there was concern for necrotizing retinitis. He was treated empirically for presumed acute reti…

Presentation with peripheral retinal whitening and perivascular hemorrhages. PCR was positive for HSV. Treatment was with the intravitreal antiviral Foscarnet as well as oral Valacyclovir. On 3 months follow up there was improvement in the retinitis with peripheral atrophy that was laser demarcated…

Acute Retinal Necrosis Secondary to HSV-2 Acute retinal necrosis is a rare entity clinically defined by one or more foci of retinal necrosis in the peripheral retina with circumferential spread and rapid progression in the absence of therapy. It typically includes an occlusive vasculopathy and prom…

Acute Syphilitic Posterior Placoid Chorioretinitis A 56-year-old Hispanic male with past medical history of gout presented to the emergency room with a “purple spot” in his right eye for the last four days. Examination was significant for best corrected visual acuity (BCVA) 20/70, no anterior c…

Acute Syphilitic Posterior Placoid Uveitis An adult patient presented to the Bascom Palmer emergency room for evaluation of five days of bilateral painless vision loss and floaters. On slit lamp examination he did not have any conjunctival injection or anterior chamber cell or flare. Dilated fundus…

Acute Zonal Occult Outer Retinopathy (AZOOR) A 31-year-old male presents with eye redness, foreign body sensation, and blurry vision in both eyes, worse in the right eye. On exam he is found to have follicular conjunctivitis in both eyes with sub epithelial infiltrates on the right cornea. His conj…

Age Related Macular Degeneration RPE tears occur in AMD as part of the normal disease progression. They are usually associated with vascularized pigment epithelial detachments at a rate of 10%. RPE tears are also associated with Central Serous Retinopathy, Retinal Angiomatous Proliferation, Polypoi…

Age-Related Macular Degeneration We present an elderly patient with new onset visual distortions in the right eye. Vision is 20/30 OD, 20/20 OS. She is diagnosed with exudative Age-related Macular Degeneration (AMD) in the right eye and non-exudative AMD in the left eye. Swept Source OCT Angiograph…

Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy A patient with no family history of retinal disease presented to the Bascom Palmer emergency room with 4 days of floaters in her right eye. Her VA was 20/30 and her intraocular pressure was normal. She was found to have vitreous hemorrha…

Autosomal Recessive RPE65-Deficient Leber Congenital Amaurosis A 17-year-old male with a biallelic RPE65 mutation resulting in autosomal recessive Leber Congenital Amaurosis is referred for evaluation for subretinal gene therapy with voretigene neparvovec-rzyl. Baseline evaluation was remarkable fo…

Fundus photo with exudates in a stellate pattern surrounding macula. OCT showing the hyperdense exudates in the outerplexiform layer.

Right eye with central retinal artery occlusion and left eye with superior branch retinal artery occlusion.

Bilateral Subacute/Chronic Endophthalmitis Leading to Complex Combined Retinal Detachment A patient with past medical history of chronic sciatica and recurrent skin abscesses presented to an outside hospital with positive blood, urine, and skin abscess cultures positive for methicillin sensitive st…

Fundus photos with creamy yellow sub-retinal lesions emanating radially from the nerve. FA OS with late staining and ICG with delineated hypocyanescent spots in the mid and late phases. The patient was HLA-A29 positive. ERG was used to monitor, assessing the B wave for a delayed 30hz flicker time.

Birdshot Chorioretinopathy The patient presented with blurry vision, flashes of lights and floaters in the right eye that progressively worsened and eventually affecting her fellow eye. She was found to have signs of inflammation on clinical examination, which was further supported by imaging modal…

Branch Retinal Artery Occlusion A patient with a past medical history of fusiform aneurysm of the right anterosuperior M2 trunk measuring 7 x 15 mm underwent a pipeline assisted coil embolization of the right middle cerebral artery M2 fusiform aneurysm, which led to almost complete obliteration of …

C2orf71 Retinitis Pigmentosa A patient presents to the neuro-ophthalmology clinic for evaluation of chronic progressive vision loss over many years. There is high suspicion for a genetic disorder given findings of bilateral symmetric nerve pallor, diffuse chorioretinal atrophy, and attenuated vascu…

A patient with a history of progressive blurry vision in her left eye for 2 years prior to her presentation. She has no significant past medical except for consuming an over the counter oral tanning pills for a period of 7 years that was stopped 2 years prior to her presentation. Her exam was notab…