A five-week-old full-term male with a history of seizures and birth trauma underwent ophthalmology screening. Initial eye examination revealed vitreous hemorrhage. Subsequent examination under anesthesia with multi-modal imaging revealed vitreous hemorrhage and an intra-retinal mass with numerous sac-like aneurysmal dilatations, consistent with retinal cavernous hemangioma (RCH). The patient had no clinical evidence of tuberous sclerosis, and a comprehensive systemic workup (cardiac, renal, dermatologic, and neurologic) did not reveal an underlying etiology of seizure disorder in this patient. Vitreous hemorrhage in a neonate is an atypical presentation of RCH. Clinicians should be aware that birth trauma may lead to vitreous hemorrhage from RCH. This is the first description of this rare retinal vascular tumor in a newborn.
Presentation Date: 11/12/2020
Issue Date: 04/30/2021