Retina and Vitreous Diseases

Fundus photos showing sheathing of the major and minor vasculature. Fluorescein angiography with small vessel vasculitis with diffuse temporal non-perfusion.

Fundus photograph of the left eye demonstrating macular telangiectasia with surrounding exudates in the fovea and temporal macula.

MacTel Type 1 A patient presented with chronic cystoid macular edema (CME) in the left eye. His BCVA OS was 20/60. Despite prior long-term interventions with intravitreal steroids and anti-VEGF agents (ranibizumab and aflibercept), the macular edema persisted, prompting the exploration of alternati…

Macular Neovascularization Secondary to Best Disease in a Pregnant Female A patient with a history of Best Disease mutation in BEST1 presented with a sudden onset of blurriness and distortion in her left eye (OS) for three weeks. The patient's family history reveals genetic and visual implications,…

Macular Telangiectasia Type 1 - Torpedo Maculopathy This is a case of a middle-aged man presenting with a decrease in vision in his left eye for a period of 2 months. On fundus examination the patient presented with a pigmented macular asymptomatic lesion in the right eye and vascular telangiectasi…

Microcephaly with or without Chorioretinopathy, Lymphedema or Intellectual Disability (MCLID) This patient with past medical history of microcephaly, lymphedema and mild cognitive delay, was referred for retinal evaluation. Ophthalmological evaluation was notable for hyperopia and extramacular pigm…

A 50-year-old patient presenting asymptomatically with 20/30 vision was found to have yellow outer retinal lesions bright on autofluorescence. Genetic testing confirmed a mutation in the RDS gene. Often this can simulate Stargardt’s disease which has a mutation in the ABCA4 gene. There is no trea…

Multifocal Uveal Melanoma in Setting of Oculodermal Melanocytosis A healthy young patient with prior history of myopia OU presents with sudden-onset decreased vision in the right eye. On presentation, patient’s exam was notable for visual acuity of HM in the right eye and 20/20 in the left eye. I…

Multiple Evanescent White Dot Syndrome (MEWDS) An otherwise healthy young patient without significant medical or ocular history presents with 3 days of acute-onset decreased vision in the right eye. On presentation, patient’s exam was notable for visual acuity of 20/50 in the right eye and 20/20 …

Myopic degeneration patches of severe retinal and choroidal atrophy, lacquer cracks, a tilted disc and lattice degeneration.

Myopic Traction Maculopathy This is a case of an elderly woman with pathologic myopia referred for asymptomatic worsening macular schisis in the right eye on optical coherence tomography (OCT). Fundus examination showed pathologic myopia and a posterior pole staphyloma. She was diagnosed with myopi…

Non-Paraneoplastic Autoimmune Retinopathy A patient presented to the uveitis clinic for progressively decreasing vision in both eyes. She first noticed difficulty in seeing at night and later also developed flashes and halos of light. Best-corrected visual acuity was 20/40 in the right eye and 20/8…

Paracentral Acute Middle Maculopathy (PAMM) Associated with Antiphospholipid Antibody Syndrome and Impending Central Retinal Vein Occlusion We report a case of paracentral acute middle maculopathy (PAMM) associated antiphospholipid antibody syndrome, and impending central retinal vein occlusion (CR…

Paraneoplastic Autoimmune Retinopathy A patient with a history of advanced ovarian cancer presented with flashes, glare and peripheral visual field loss of 10 months duration. Best-corrected visual acuity was 20/30 in the right eye and 20/40 in the left eye with normal intraocular pressures in both…

Penetrating Open Globe Injury with Retained Intraocular Foreign Body, Left Eye A patient presented with acute decreased vision in the left eye after motor vehicle accident. The patient stated in the accident his car spun out and airbags deployed. Upon presentation, visual acuity was 20/25 in the ri…

Pentosan Polysulfate Associated Maculopathy A patient presents with a history of difficulty reading and progressive blurry vision in both eyes prior to her presentation. Patient has a significant history of interstitial cystitis with long term use of Pentosan Polysulfate Sodium for 20 years. Her ex…

PFO liquid in the anterior chamber after retinal surgery. This caused some corneal edema and required removal.