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Large sub-ILM hemorrhage leading to sub-retinal exudative changes in a patient with leukemia.

Squamous Cell Carcinoma of the Lacrimal Sac A patient presented to the emergency department for a history of tearing on the right eye and medial canthal mass. He had a history of chronic sinus pain for months, initial examination was notable for increased tear lake on the right eye, along with an i…

Group E retinoblastoma

Recurrent Locally Advance Morpheaform BCC A patient presented to our clinic with a 5 month history of worsening ptosis and induration of the right upper eyelid. She had a past medical history significant for chronic UV exposure, and a previously completely excised infiltrating/morpheaform basal cel…

PAM and OSSN This case presents a 67-year-old gentleman who was referred for a pigmented lesion. The HR-OCT suggested that this was not simply a small area of PAM, but rather demonstrated an epithelial hyper-reflectivity and thickening with an abrupt change from normal to mildly thickened epitheliu…

Orbital Venous Lymphatic Malformation A patient presented to the ER complaining of 2 days of increasing pain and swelling behind the left eye. Of note the patient reported that as a teenager he was previously treated for an orbital tumor. On exam he was found to have massive proptosis, hyperglobus …

Orbital Sarcoidosis A patient presented with three months of left eye swelling and pain. He was found to have periorbital firmness and fullness, proptosis, and conjunctival chemosis. He underwent computed tomography imaging of the orbits with contrast, which demonstrated an ill-defined, irregular a…

Orbital Rhabdomyosarcoma - Recurrence A young patient with notable past ocular history of orbital rhabdomyosarcoma, s/p chemotherapy with vincristine, dactinomycin, and cyclophosphamide, and proton beam radiation presented to Bascom Palmer ED with 2 days of blurry vision and “seeing everything gr…

In this module, we will look at:




Orbital Oncology


Conjunctival Oncology


Retinal Oncology


Uveal Oncology

Metastatic Melanoma; Side Effect of Immune Checkpoint Inhibitor A patient with a history of recurrent metastatic conjunctival melanoma presented with a left upper lid orbital lesion and pigmented lesion in the medial fornix. The original conjunctival melanoma was originally excised in an outside ce…

Melanocytoma with Vitreous Seeding A patient with 7 years of blurry vision in the right eye presents to clinic for evaluation. He reports no recent acute changes in vision and no precipitating events in the past. He noticed the blurry vision incidentally while driving when he covered his left eye. …

This patient presented with 1 month of left eyelid swelling. MRI showed infiltration in the periorbital soft tissues. Absolute CD4 count was 27 and the diagnosis was made with immunohistochemistry positive for HHV8. The patient was started on HAART therapy, the local lesions were treated with nitro…

Invasive Cutaneous Melanoma of the Eyelid A patient presented to clinic for a long-standing history of a left lower eyelid/ cheek lesion with more recent growth. He had a history of multiple previously resected basal cell carcinomas of the face, neck and scalp. Initial examination was notable a lef…

The patient presented with an enlarging lower eyelid lesion for 2 months. There was irregular pigmentation without ulceration or madarosis. Biopsy confirmed an intradermal nevus.

Granular Cell Tumor A patient was referred by an outside ophthalmologist for evaluation. The patient reported having headaches, double vision, and eye bulging for 3 months. Her exam was notable for restricted extraocular movements in her left eye on abduction and adduction. Her slit lamp exam was n…

Diffuse Iris Melanoma A patient presented for evaluation of multiple melanocytic lesions of the right iris that were noticed a few months prior. She was found to have a visual acuity of 20/25 in the right eye and 20/20 in the left eye, with intraocular pressures of 19mmHg in both eyes. Slit lamp ex…

Conjunctival melanoma treated with I-125 brachytherapy.

A large pigmented nasal growth with vascularization. This case was treated with surgery using a 'no touch technique' excisional biopsy with 4 mm margins and amniotic membrane tissue placement.