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Ranibizumab Port Delivery System Exposure A patient presented to Bascom Palmer clinic with redness and decreased vision in the right eye. She had a history of wet age-related macular degeneration managed with many years of intravitreal ranibizumab injections, and implanation of intraocular ranibizu…

Intraocular Foreign Body A middle-aged patient sustained a penetrating open-globe injury from an alligator bone fragment while hunting. On presentation, visual acuity was hand motions with a large corneoscleral laceration and disorganized intraocular anatomy. Imaging revealed a hyperdense intraocul…

Maternally Inherited Diabetes and Deafness (MIDD) A patient with diabetes and sensorineural deafness was referred to evaluate AMD in both eyes. She had been diagnosed with bilateral sensorineural hearing loss 10 years earlier. Genetic testing confirmed the m.3243A>G mutation in MT-TL1 gene, lead…

Secondary Intraocular NK/T-Cell Lymphoma A patient with a history of systemic NK/T-cell lymphoma, previously treated with two rounds of chemotherapy and currently in remission, presented with a six-month history of chronic uveitis in the left eye. She was initially managed with difluprednate drops,…

Macular Telangiectasia Type 2 Macular Telangiectasia Type 2 (MacTel Type 2) is a rare, progressive retinal disorder characterized by neurodegeneration of Müller cells, leading to central vision loss and macular atrophy. We present a case of a patient with a 4-year history of gradual, bilateral vis…

Muckle-Wells Syndrome A patient with a past ocular history of retinal vasculitis with subretinal hemorrhage, vitreous hemorrhage, herpetic keratitis, and cataract surgery presented to the emergency room due to sudden onset blurred vision and retrobulbar pain of the left eye. The patient reported lo…

Retinitis Pigmentosa A patient presented with progressive loss of vision since eight years of age. His BCVA in the right eye was 20/300 and the left eye was 20/800. Anterior segment examination showed posterior subcapsular cataract in both eyes. Posterior segment examination showed bony spicule pig…

A patient with bilateral progressive vision loss who presents to clinic for evaluation. Patient's vision loss started in childhood, with initial vision being 20/200 in both eyes. Fundus photos show optic nerve pallor, macular atrophy and extensive pigmentary changes in the periphery. Genetic testin…

A patient presented complaining of decreased vision in the right eye for the past 3-4 months. Best-corrected visual acuity was 20/80 in the right eye. Posterior segment examination revealed a macular hole and cystoid macular edema. (B) Optical coherence tomography demonstrated a macular hole with v…

Cyclodialysis Cleft A patient with a history of sudden vision loss (hand motion) in the left eye following an intravitreal injection for chronic central serous retinopathy (CSR) presented with reduced vision five months later. At the time of presentation, the left eye's visual acuity had improved t…

A patient with Fabry disease. Slit lamp photos show tortuous conjunctival vessels, corneal verticillata, and cataract. Fundus photos show tortuous vasculature.

Retinal Artery Macroaneurysm An elderly patient with history of uncontrolled hypertension presented with acute onset vision loss of the left eye. Vision was noted to be 20/25 and 20/60. Exam and imaging showed focal macular hemorrhage with significant intraretinal fluid. Intra-vitreal bevacizumab w…

Endogenous Candida Endophthalmitis Endogenous endophthalmitis is an ophthalmic emergency that requires prompt recognition, treatment, and full systemic workup to identify the source of the infection. This case describes a male with a past medical history of diabetes, hypothyroidism, and nephrolithi…