52-year-old male with Stage IV extranodal MALT lymphoma who initially presented with paranasal and perioribtal disease. He failed treatment with multiple chemotherapeutic agents and represented with decreased VA 20/40 and 20/80 thought to be due to diffuse choroidal metastasis. Repeat lacrimal gland biopsy demonstrated transformation to high-grade diffuse large B-cell lymphoma. The patient was initiated on salvage chemotherapeutic regimen and demonstrated improvement on follow-up PET-CT scan. Autologous stem cell transplant was recommended, but ultimately the patient may not be able to undergo treatment due to social issues.
Presentation Date: 02/13/2020
Issue Date: 08/01/2020