Topic outline

  • Grand Rounds

    The purpose is to report the changes in choroidal thickness (CT) and the choroidal vascularity index (CVI) measurements using widefield SS-OCT imaging in a patient undergoing treatments that should alter choroidal blood flow.

    Patient underwent 12x12mm SS-OCT angiography scans centered on the fovea. The scans consisted of 500 A-scans per B-scan with 500 B-scans repeated twice at each position. Patient had undergone internal carotid stenting secondary to carotid stenosis. Imaging was performed before and after the procedure. Automated choroidal segmentation algorithms applied to OCT structural scans were used to measure the choroidal thickness (CT) and choroid vascularity index (CVI) throughout the12X12mm scan area.

    The patient had a history of intermediate AMD and underwent bilateral carotid stenting for carotid stenosis. The patient had a pre-treatment mean CT measurement of 269.2μm that decreased to 237.5μm and a pre-treatment mean CVI of 0.62 that decreased to 0.60 after the stenting procedure. Right eye CT and CVI did not show significant change.

    The ability to use widefield SS-OCT imaging combined with automated algorithms to assess changes in CT and CVI measurements in diseases that affect choroidal blood flow should lead to a better understanding of choroidal autoregulation and help clinicians decide when best to intervene and help assess the benefits of various treatments. Additional patients are currently being imaged and followed.

    Presentation Date: 02/06/2020
    Issue Date: 08/01/2020