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Cataracts and Intraocular Lenses
Comprehensive Ophthalmology
Corneal and External Diseases
Glaucoma
Neuro-Ophthalmology
Ocular Oncology
Ophthalmic Pathology
Ophthalmic Plastic and Reconstructive Surgery
Pediatric Ophthalmology and Strabismus
Retina and Vitreous Diseases
Uveitis
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CA121825NC
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https://bascompalmerlearn.org/pluginfile.php/38037/mod_resource/intro/12.18.25_Dr.Seely_Conjunctival%20Amyloidosis_Final.mp4
Abstract
A patient presented with a raised, well-demarcated, yellow-ish lesion of the left lower palpebral conjunctiva, which had been present for 2 months. The lesion had previously been treated as a chalazion without improvement. She had no systemic systems. Anterior segment OCT demonstrated a thickened, hyperreflective sub-epithelial lesion and pathology from biopsy showed deposition of amorphous eosinophilic PAS- and Congo Red-positive material demonstrating apple-green birefringence, consistent with amyloidosis. The patient was referred to hematology-oncology for systemic workup which is pending.
Presentation Date:
12/18/2025
Issue Date:
03/20/2026
Select activity Presenter: Kai R. Seely, MD, MHSc
Presenter: Kai R. Seely, MD, MHSc
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Select activity Faculty Discussant: Sander R. Dubovy, MD
Faculty Discussant: Sander R. Dubovy, MD
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Select activity Faculty Discussant: Brian C. Tse, MD
Faculty Discussant: Brian C. Tse, MD
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